Well it depends what you mean by 'prestige', as that would be the AMEX Centurion, but it's not really a points collectors card per se given the $5K annual fee.
The AMEX Platinum charge card is probably the most 'prestigious' personal card in terms of the perks and benefits it brings - I get full value from the perks, but i'm a small business owner, without traditionally much 'status' on airlines or hotels, so it works well for me, but others don't get the value I do, from the looks of others' comments on the card, esp. since the AMEX devaluation in mid-April.
Others might like to comment on the top-end Citi card, or even the BOQ Speciality cards, as others that come to mine.