General Medical issues thread

I had to look up ganglion to see it wasn’t the clap. Once I knew that it was a cyst I felt around my hands and yes there are a couple that exist that were not there 25 years ago. Just part of the fun of getting older.
I had a ganglion cyst in my upper wrist many years ago. So not an old people thing. It grew really large. A remedy used to be to hit it with the family bible. Mine started impededing wrist movement so it was removed surgically 20 years ago.
 
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There is no direct test for methanol or ethanol. Measurement relies on the sample undergoing controlled chemical reactions.
Yes, understand that. The thing that needs to be proven for a denial of claim is the level of alcohol intoxication - ie how many alcohol drinks did they consume, ie were they drunk.
 
how many alcohol drinks did they consume, ie were they drunk
Sprry i thought you were referring to something else.

Should be easy enough to prove one way or another. Just a blood alcohol test will do or in the absence of that ofher evidence such as a bar tab and/witness statements

The TI I usually use specifies a BAC of 0.19 which is nearly 4x the usual 0.05

A positive BAC wont affect a methanol poisoning diagnosis. I suspect in some/many of these cases there will also be other substances other than methanol including ethanol, illegal drugs etc. standard management include testing for all sorts of substances one would typically find in a cohort of patients like these

What might be problematic would be a BAC > 0.19 + methanol poisoning. Interestingly when using ethanol infusion to treat methanol poisoning the target BAC is 0.15. So being drunk is protective but it only buys time - need stomach pumped, then dialysis, maybe 4MP infusion etc etc

IMG_4802.jpeg
 
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Whilst I have a GP, I can easily go 2+ years with zero need to visit them as have no ongoing health issues that need continuous treatment.

So I guess I have to be ok with an autopsy if I drop off this mortal coil before deteriorating to the stage I need to be at the GP every 2-3 months like my parents.
Coroners very rarely request autopsies in my experience. They try to go the low effort route if at all possible. Any medication? Any investigation for blood pressure or cholesterol in the last 20 years? Boom, heart attack, signs the certificate.
There is no direct test for methanol or ethanol. Measurement relies on the sample undergoing controlled chemical reactions.
Actually we (and I imagine all larger laboratories) do measure it directly by GC-MS. I always got phone calls about this at 4pm Friday as a chemical pathology trainee.
 
You are absolutely correct. Do most hospital labs have them?
All the large referral labs will; very common analyser for therapeutic drug monitoring, volatile measurement, lots of metabolics.

Your regional centres are unlikely to have one but all the centrals ones will.

For the regional labs, you can have a guess based on the anion gap ... remember the MUDPILES acronym from med school! For the non medical, the anion gap is calculated based on a bunch of very commonly measured blood parameters. If there's a big gap, it means there is something in the blood that isn't being measured - this could be methanol (amongst others).
 
All the large referral labs will; very common analyser for therapeutic drug monitoring, volatile measurement, lots of metabolics.

Your regional centres are unlikely to have one but all the centrals ones will.

For the regional labs, you can have a guess based on the anion gap ... remember the MUDPILES acronym from med school! For the non medical, the anion gap is calculated based on a bunch of very commonly measured blood parameters. If there's a big gap, it means there is something in the blood that isn't being measured - this could be methanol (amongst others).
I think I slept through MUDPILES in med school but your explanation resulted in some creaky turning of a few cogs in my brain @k_sheep !😂
 
All the large referral labs will; very common analyser for therapeutic drug monitoring, volatile measurement, lots of metabolics.

Your regional centres are unlikely to have one but all the centrals ones will.

For the regional labs, you can have a guess based on the anion gap ... remember the MUDPILES acronym from med school! For the non medical, the anion gap is calculated based on a bunch of very commonly measured blood parameters. If there's a big gap, it means there is something in the blood that isn't being measured - this could be methanol (amongst others).
I have multiple blood tests done each month and a whole new ones every 12 months and have always wondered what the anion gap was. Now I know what it is but I don't understand what it is. Progress methinks.😂
 
I have multiple blood tests done each month and a whole new ones every 12 months and have always wondered what the anion gap was. Now I know what it is but I don't understand what it is. Progress methinks.😂
And watching one of those medico programmes on Netflix they just doscussed the anion gap. What are the chances of that after 8 years of blood tests and never doscussed the anion gap before.
 
All the large referral labs will; very common analyser for therapeutic drug monitoring, volatile measurement, lots of metabolics.

Your regional centres are unlikely to have one but all the centrals ones will.

For the regional labs, you can have a guess based on the anion gap ... remember the MUDPILES acronym from med school! For the non medical, the anion gap is calculated based on a bunch of very commonly measured blood parameters. If there's a big gap, it means there is something in the blood that isn't being measured - this could be methanol (amongst others).
I thought it was the osmolar gap for methanol...or is it both?
 
My good news, my LDH numbers are going down. After the last PET scan did not indicate any tumour activity I suggested perhaps the Efudix cream I was using over repeated courses was the cause. I stopped the last course a few weeks ago. At my Friday pre-infusion meeting with my specialist she agreed that could be the answer.
 

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