The COVID-19 vaccine rollout in Australia has begun

[Quickstatus]

the longer you wait between jabs, the more effective the vaccination is

Against that is the fact that a 2jab is more protective than a 1jab in the context of an active pandemic hotspot.

Basically get a 3jab but the 3rd should be different.

 

[Lynda2475]

and Todays presser confirms Vic special access:

"The state is receiving 88,000 doses of the vaccine on Sunday, which are being redirected from community pharmacies."

So people obviously failing to use the pharmac_ channel; in Vic, hence need to have Moderna at state hubs.

Hopefully other states will now be afforded the same privilege of having Moderna in the very popular hubs.

 

[Lynda2475]

Oops, this isnt great news:

MSN

 

[jakeseven7]

More good news to drive vaccinations

——

New mandatory vaccinations for thousands of Victorians

Premier Daniel Andrews has announced “hundreds of thousands” of authorised Victorian workers will soon be required to be vaccinated in order to keep working.

From October 15, all workers on the Authorised Worker list will be required to have their first dose of a Covid vaccine in order to continue working on site. They will need to be fully vaccinated by November 26.

This rule applies to both Melbourne and regional Victorians.

Thousands hit with new mandatory vaccines

Welcome to Friday’s coverage of Australia’s Covid-19 situation.

www.news.com.au

 

[lakeman]

Basically get a 3jab but the 3rd should be different.

You should preface this by saying this is your unsupported opinion.
If you have special qualifications to say this , you should declare them together with supporting studies.
There is too much disinformation being disseminated and presented as common sense or fact.

 

[lovetravellingoz]

and Todays presser confims

"The state <Vic?>is receiving 88,000 doses of the vaccine on Sunday, which are being redirected from community pharmacies."

So people obviously failing to use the pharmac_ channel; in Vic, hence need to have Moderna at state hubs.

It is impossible for people to get a Moderna Vaccination in pharmacies that are not actually set up to deliver Moderna as yet, as well as ones that do not yet have the required throughput.

The Commonwealth were the ones that decided to deliver a bulge of Moderna doses over a short time period, and then did not successfully commission the capacity to inject it in the required LGA's within its own announced timeframe.

This was the short-term plan announced by Greg Hunt

Greg Hunt Media Release 12 Sept.​

​

Residents in Melbourne’s north and west will benefit from additional vaccines and a rapid expansion of vaccination sites across the region as part of a three-week vaccination blitz.​

​

To assist these communities and all Victorians, the Commonwealth will surge more than 417,000 doses of Pfizer and Moderna vaccines to Victoria in September.​

​

The surge will consist of:​

​

• More than 127,600 additional Pfizer doses will be delivered by the last week of September to 532 Victorian GPs, increasing their vaccine allocation from 600 doses a fortnight to 900 doses a fortnight.
• More than 108,700 additional Pfizer doses will be delivered to the Victorian Government as part of Operation COVID Shield.
• An additional 180,700 Moderna doses will be delivered to Victorian pharmacies over the next two weeks. This is in addition to 119,510 Moderna vaccines that were already scheduled for Victorian pharmacies this month.
• This is in addition to uncapped allocations of AstraZeneca available to Victorian GP’s, pharmacies and the state government.

So based on what the Commonwealth announced:

• 3 week blitz that they were joining which would be 12 Sept = to be achieved by this Sunday 3rdOct = Will not be
• So all those Moderna doses were meant to be delivered by by the end of Sept.
• No Moderna was planned to go to the State Channel
• Residents in Melbourne’s north and west will benefit from additional vaccines and a rapid expansion of vaccination sites across the region as part of a three-week vaccination blitz = abject failure by the Commonwealth to actually get up and running enough Pharmacies within the north and west to achieve their stated goal.

So given that failure in the Commonwealth Primary care channel in Victoria initially 32,000 doses (Vic Gov volunteered to inject Moderna as they stated they doubted the Commonwealth's ability to commission the required throughput) and now 88,000 Moderna doses have been transferred to the state channel as opposed to:

• just leaving the doses sitting in storage for another fortnight or so (So a month late in total).
• not using them in the priority LGA's. (Not that the other Pharmacies probably could have coped with the throughput in 3 weeks anyway

The Commonwealth failed to deliver what it stated it would do it when it announced it would surge Moderna doses over a 3 week period, and failed to open up and commission the Pharmacies vaccination capacity to actually achieve this timeline.

Moving 130,000 doses to the State Channel helps to recover, but as that 88,000 will go into arms after the 3rd the total number of Moderna doses will be later than they should have been.

Hopefully other states will now be afforded the same privilege of having Moderna in the very popular hubs.

Privilege? What other jurisdiction would want doses delayed by over two months, only to then have them further delayed by the Commonwealth not actually having set up enough capacity to deliver those doses?

These doses are part of the make-up from August doses of Pfizer that were differenced from VIc to NSW. The so called "brought-forward" doses. It turned out that the Commonwealth did not actually have time-travel and so the "brought- forward" Pfizer was actually taken from Vic and Qld.

The Pfizer doses are now in large part being made good over two months later, but not as Pfizer, but as Moderna. And despite it being the Commonwealth's own announced plan they have failed to ramp up enough Pharmacies in the hotspot LGA's to inject those doses.

 

[Quickstatus]

You should preface this by saying this is your unsupported opinion.

You are right that it is my opinion but supported by data out of Spain and Canada that mixed and matched

Here in AU, SV has been ordered apparently to be a booster.

 

[Quickstatus]

Commonwealth's own announced plan they have failed to ramp up enough Pharmacies in the hotspot LGA's to inject those doses.

Hard to know for sure who was the rate limiting step or maybe there was none.

 

[drron]

Though there is also a lot of data saying that a third dose of Pfizer leads to higher antibody levels than after the second plus data from the UK that having a third dose of AZ gives much higher antibody levels than that seen after the second dose with less side effects.

 

[HappyFlyerFamily]

Hopefully with today's announcement of a opening international border date of some time in November, its another carrot to those in covid-zero states to want to get both jabs by say 30 November.

 

[mviy]

341,129 doses were administered yesterday which I think would put those numbers released today as the second highest day on record for COVID-19 vaccinations in this country.

For 12-15 year-olds there is 37.91% first dose and 2.31% fully vaccinated. There was a big jump in fully vaccinated for 12-15 year-olds from 0.68% the day before to 2.31% so there must be a number starting to come due for their second doses. The fully vaccinated number for this age group should climb rapidly over the coming weeks.

SA and VIC have both gone past 50% fully vaccinated for 16+ and TAS has reached 80.26% fully vaccinated for 70+.

VIC has reached 90.12% first dose for 50+.

 

[Quickstatus]

leads to higher antibody levels

(Not directed at @drron)
Don’t forget there are 2 branches to the immune system - T and B cells.
Antibodies are produced by descendants of B cells (humoral mediated immunity)
T cells are also important. There are a variety - helper T, memory T, killer T (cell mediated immunity)

B &T work together in a complex interplay

Both antibody and T cell response re Covid Vax have been shown to improve with 3 rather than 2jab.

Studies in Spain and Canada seem to show the improvement is better when mixed and matched. Israel on the other hand only using one type for its 3jab also showing improvement.

 

[drron]

Ah

(Not directed at @drron)
Don’t forget there are 2 branches to the immune system - T and B cells.
Antibodies are produced by descendants of B cells (humoral mediated immunity)
T cells are also important. There are a variety - helper T, memory T, killer T (cell mediated immunity)

B &T work together in a complex interplay

Both antibody and T cell response re Covid Vax have been shown to improve with 3 rather than 2jab.

Studies in Spain and Canada seem to show the improvement is better when mixed and matched. Israel on the other hand only using one type for its 3jab also showing improvement.

But have you read the studies from the UK where the AZ has a better T cell response than Pfizer.A good article in the FT but it is behind a pay wall unless you have a subscription.But mentioned here.

AZ vaccine 'may give longer immunity', suggests UK drugs giant boss

Pascal Soriot, chief executive of the UK pharmaceutical giant, told the Daily Mail that he is hoping for concrete data this autumn that proves its jab produces strong 'T cell immunity'.

www.dailymail.co.uk

AstraZeneca's COVID Vaccine May Provide Lifelong Protection

The Oxford-AstraZeneca jab creates training camps in the body for search-and-destroy T-cells which can kill even the new variants apart from providing powerful antibody response.

www.medindia.net

 

[lovetravellingoz]

Vic is now at 81.5 % First Dose and 51.5% Second Dose.

That is salient as it was about then that NSW Cases numbers started to decline.

However generally speaking in NSW, Sydney is higher than the Regions, whereas in Vic the Regions have a higher vaccination rate than Melbourne.

So the average for Melbourne where most of the cases are will be lower than 81.5 % First Dose and 51.5% Second Dose.
However within a week most of Melbourne should be at or above that figure.

Hume is which is the main hotspot LGA has now shot up to 80% First Dose (3 weeks ago Sept Hume was at 48.2%/ 26.0%). Second dose probably will take over a week to get to 50 % (LGA weekly update will be out by Monday). However the main hotspot suburbs still had relatively low Second Dose Rates of 35-42% last Monday. However the change from this coming Monday at Vic State Hubs/Pop-ups for Pfizer back to 3 weeks spacing of the second dose should cause a surge in the second dose rate.

So if the trend in Sydney repeats In Melbourne one would expect to see daily cases declining in the near future.

 

[mviy]

79.01% first dose for 16+. In 2 or 3 days we should be up to 80% first dose.

89.8% first dose for 50+. That figure should be past 90% when today's numbers are released tomorrow.

>95% first dose for 70+ and 79.54% fully vaccinated for the same group. When today's numbers are released tomorrow that fully vaccinate figure should be past 80%.

12-15 has reached 40.12% first dose, over half-way to 80%. NSW is at 56.1% first dose and VIC at 48.82% first dose for this age group.

80-84 has reached 80.4% fully vaccinated, the second 70+ age group to go past 80%.

65-69 has reached 70.3% fully vaccinated. Every age group 65-69 and up has gone past 70% fully vaccinated.

50-54 and 55-59 have 69.8% fully vaccinated. When today's numbers are released tomorrow they should go past 70%.

30-34 has reached 70.5% first dose and 40.7% fully vaccinated.

TAS should go past 60% fully vaccinated for 16+ when today's numbers are released tomorrow. NSW currently at 66.5% should go past 2/3 fully vaccinated when today's numbers are released tomorrow.

Shockingly NSW's fully vaccinated figure of 66.5% for 16+ is higher than WA's first dose figure of 65.94%. The situation's not much better for the NT and QLD. NSW's fully vaccinated is just below NT's first dose figure of 66.53% and not far below QLD's first dose figure of 66.96%.

NT has reached 70.14% fully vaccinated for 70+, the last state or territory to go past 70% for this age group.

Post automatically merged: Oct 2, 2021

Vic is now at 81.5 % First Dose and 51.5% Second Dose.

Getting that per cent or two past 80% gives confidence that 80% fully vaccinated will be reached too. Hopefully within a few weeks or so that first dose figure is pushing up towards 90%.

 

[mviy]

VIC government is reporting a strong first rate of first doses still. 82.6% first dose for 16+ and 51.9% fully vaccinated.

 

[Batterytraveller]

VIC government is also reporting:

For the 12+ population it’s 80% single dosed, indicating how fast 12-15 year olds have been added to the program.

Which just goes to show that no one needs to worry about moving goalposts, there’s only a couple of days difference in the two numbers and the more vaxxed the better.

 

[mviy]

If we can get to 90% first dose in VIC that should make it easier for them to stick to the current plan as fully vaccinated numbers will continue to climb even after 80% is reached.

If vaccination rates were stalling that would signify a bigger problem.

We can see in NSW clearly that as vaccination rates soar case numbers should stabilise or even come down whilst restrictions remain in place.

 

[Quickstatus]

But have you read the studies from the UK where the AZ has a better T cell response than Pfizer.

A few other technical papers also suggest that too - at the 1Jab level.

Best way to envisage antibody and T cell immunity is this:
The antibodies are very specific - like a lock and key. They latch on better if the antigen or amino acid sequence matches it exactly and less so if there are differences.
So in viral variants, the antibody response might not be as effective.

However T cells are very sensitive to the "bigger picture" and recognise larger viral fragments and are therefore less susceptible to viral variations.

Remember the Covid "cytokine storms"?. These are caused not so much by your antibodies, but by your T cells recognising the intruder and they ring up their mates for backup, specifically a special type of white blood cell called a "Natural Killer" NKcell who swarm in and kill in a largely indiscriminate way.
Basically the T cells are the Special forces who ring in an air attack and the NK cells comes in to carpet bomb the place.

 

[jakeseven7]

Has anyone seen the weekly VIC LGA level vax rates yet? I need for a work report… can’t see in the regular places yet just checking I’m not going mad!