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- Oct 13, 2013
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Discussions with a colleague with quantitative Covid antibody assays:
Basically even if the assay antibody levels are zero, it does not necessarily indicate protection has waned or non existent. In other words, high antibody levels can be predictive for protection but no antibody does not mean no protection. Degree of protection and what is high or adequate is not known.
Basic understanding of immunology supports this - particularly the function of Memory B and Killer T cells which are not reflected in antibody tests.
Basically even if the assay antibody levels are zero, it does not necessarily indicate protection has waned or non existent. In other words, high antibody levels can be predictive for protection but no antibody does not mean no protection. Degree of protection and what is high or adequate is not known.
Basic understanding of immunology supports this - particularly the function of Memory B and Killer T cells which are not reflected in antibody tests.
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