I believe I have travelled five times into a Do Not Travel zone: Algiers Kasbah, Zimbabwe, Lebanon, Songkla and Nagorno Karabakh. I did not believe any of these presented any major threat to life but the warnings did make me do some research. The biggest consideration was that this travel invalidated travel insurance but on each occasion the travel was for three days max and was close to areas outwith the Do Not Travel area. The current warning os on a lesser level, but there is a real threat of borders closing and being forced into quarantine - with little prospect of insurance cover. I would take that way more seriously than the "off grid" travel I have done.