In a joint Vic Gov/Monash/Doherty today a Phase 1 Clinical trial has been announced for a locally developed mRNA Vaccine. Anticipated to begin in Oct/Nov 2021 (note Professor Bolton said Oct/Nov, media release states Oct).
Professor Poulton during the press conference said that the upskilling of Victorian Pharmaceutical Manufacturers is also now to be undertaken to permit local manufacture.
This new announcement follows on from the the earlier announcements made on fostering both research and local manufacture of vaccine candidates.
From the Media Release:
Victoria has developed and will make Australia’s first local mRNA COVID-19 vaccine candidate to reach Phase 1 clinical trials – a breakthrough in medicine and manufacturing that will create jobs and save lives.
The Victorian Government confirmed today that it would invest $5 million to support Monash Institute of Pharmaceutical Sciences (MIPS) to manufacture doses of the mRNA COVID-19 vaccine for trials, which are due to start within months.
The novel mRNA-based vaccine will enable a Victorian manufacturer to develop critical manufacturing capability of mRNA vaccines for clinical trials – a level of expertise currently unavailable in Australia.
The investment is the first to be made from the Victorian Government’s landmark $50 million fund to develop the state’s mRNA manufacturing capability.
The collaboration between MIPS and the Doherty Institute reinforces the strong mRNA sector in Victoria and means we are leading the national charge to develop mRNA manufacturing capability.
The MIPS candidate is Australia’s leading mRNA vaccine candidate, delivering next-generation vaccine support for ongoing COVID protection and future pandemics, and research capabilities for new drug and medical research breakthroughs.
The MIPS vaccine has previously received $3 million from the Medical Research Future Fund to cover the costs of the Phase 1 clinical trial.
The development of mRNA capability is revolutionising medical research globally and has the capacity for broad-based application in HIV, cancer and other treatments.
Some 150 people will be involved in the clinical trials that are due to begin in October, with preliminary results expected to be available in the first half of 2022.
mRNA Victoria’s Scientific Advisory Group, led by Victoria’s Lead Scientist Dr Amanda Caples and including American luminary Dr Barney Graham and eminent Victorian infectious disease experts such as professor Sharon Lewin (Doherty Institute) and Professor Brendan Crabb (Burnet Institute), endorsed the Monash investment.
As stated by Acting Premier James Merlino
“Making COVID vaccines in Victoria will create jobs and save lives – and it’s exciting these trials will be getting underway soon.”