But there is no absolute proof that nRNA vaccines do not cause VIPIT or are safer than AZ.
With the mRNA vaccines there have also been reported cases of thrombocytopenia and bleeding.Now in HIT there are also some patients who bleed and this can include cerebral haemorrhage and so possible death.
As well the mRNA vaccines have a higher incidence of anaphylaxis which also can be fatal
I don't think there are significant reports regarding mRNA vaccine VIPIT/VITTS. That editorial was mainly about Adenovirus vaccines.
Reports of an ITP like syndrome (idiopathic thrombocytopaenia purpura for those who aren't medics- a syndrome where your platelet count drops and get tiny bleeds under the skin that look like purple dots [purpura]) associated with mRNA vaccines are not clearly significant. An article by Lee, Cines et al in the American Journal of Hematology stated regarding mRNA vaccines - "Thus, the incidence of an immune-mediated thrombocytopenia post SARS-CoV-2 vaccination appears either less than or roughly comparable to what would be seen if the cases were coincidental following vaccination, perhaps enhanced somewhat by heightened surveillance of symptomatic patients."
"Distinguishing vaccine-induced ITP from coincidental ITP presenting soon after vaccination is impossible at this time."
ITP is very different from VITTS, with ITP essentially manifested as a lack of platelet function and primary haemorrhage - such as primary cerebral haemorrhage. VITTS is primarily a problem of platelet activation, thrombosis and secondary cerebral haemorrhage from venous hypertension, venous stroke and subsequent exogenous anticoagulation.
There were 35 possible cases of central nervous system thrombosis among 54 million Pfizer vaccinations, and 5 possible cases of cerebral venous sinus thrombosis among 4 million Moderna mRNA vaccinations. This is not appreciably higher (actually lower) than the expected community rate of cerebral sinus thrombosis of 0.22 to 1.57 cases per 100,000 per year.
So the risk of an event with an mRNA vaccine is vanishing rare and is actually lower than the chance of death by lightning strike (1 in 700,000).
TM