Will you vaccinate with Conoravirus vaccine when one is available?

[CityRail]

According to reports, coronavirus vaccine is entering its final phase of testing and very soon we will have millions of coronavirus vaccine to be rolled out, hopefully from September.

By then, should a coronavirus vaccine is available, will you vaccinate it?

Personally speaking, as a 30 year old young person, I will not vaccinate myself with Coronavirus, because:

1. It is just a small flu for young people, we won't die;
2. The vaccine is rushed and I cannot guarantee if I vaccinate myself, I will be immune to Coronavirus and not get killed by the vaccine;
3. The coronavirus vaccine is just a step to reopen our borders so that we can travel overseas again.

I am not anti-vaxier, however I only think that Coronavirus vaccine is just a political ticket for politicians to explain to the public that they can now open the international borders again and ease off travel bubbles.

What do you think?

 

[HappyFlyerFamily]

Not a good example. Though I don’t think they have had the 2nd dose yet

Emergency nurse tests positive for COVID-19 eight days after vaccination

An emergency nurse in the United States has tested positive for COVID-19 just eight days after getting the vaccine.

www.news.com.au

 

[PineappleSkip]

Which is not us in Oz.

Apart from those of us who need to travel OS. More returnees are getting COVID in quarantine, which amps up the risk somewhat.

Cheers skip

 

[Pushka]

Or you could look at it this way:

1/ The people who need it most are getting it first. Which is not us in Oz. USA just set a record for deaths in a single day. UK is grim.
2/ That other countries are trialling the vaccines for us.
3/ Emergency approval means that the process is being rushed (though for good reasons in some countries). Australia does not need to rush with the higher risks.

Appreciate that but Australia will be able to manufacture the Oxford one here I understand without any negative implications for other countries. On the other hand if we wait until Autumn then Winter kicks in then we will have our own emergency. We have been preemptive until now. That has saved us. Except for this.

 

[Sprucegoose]

The vaccine development was not rushed. Their approvals were expedited and are being dispensed currently in the US and UK under emergency approvals. Their development was completed in reduced time due to their necessity for world health and economic growth. They are cheap insurance and may not work with the same efficacy for everyone. This virus is not unique with plenty of groundwork completed prior to this year - we are dealing with version 19.

A vaccine will most probably be necessary for travel. Antivaxers should download Netflix.

Should you travel to Honkers? I can’t see any health reasons why one wouldn’t. I won’t travel to Honkers sadly, however this won’t be based on health grounds.

 

[lovetravellingoz]

Appreciate that but Australia will be able to manufacture the Oxford one here I understand without any negative implications for other countries. On the other hand if we wait until Autumn then Winter kicks in then we will have our own emergency. We have been preemptive until now. That has saved us. Except for this.

Well you needed a crystal ball to know which of the hundreds of candidates would be first to be deployed. The Fed Gov backed two in a big way and contracted for their manufacture here. One did not make it, but the other is one of the early ones to be deployed.

So yes they are manufacturing here plus also importing some of the Pfizer as well. However it does take time to manufacture.

Also one of the two vaccines ordered by the Federal Gov to be manufactured in Australia is not being proceeded with. So that will reduce manufacturing capacity.

Mr Hunt said he spoke with the local head of AstraZeneca recently and confirmed the Australian Government's supplies of the vaccine should complete final assessment from the Therapeutic Goods Administration in coming weeks and Australians should be fully vaccinated by October 2021.

Australian vaccine plans 'ahead of schedule'

www.9news.com.au

 

[drron]

Though the fact that CSL will not be manufacturing the QLD vaccine now should increase capacity for the manufacture the Oxford vaccine not decrease it.
That is opf course unless there are negotiations going on to manufacture another of the vaccine candidates.

 

[Pushka]

Australians should be fully vaccinated by October 2021.

Australian vaccine plans 'ahead of schedule'

www.9news.com.au

And that was great to read recently. Clearly going full on for the Oxford one because the other one is complicated logistically and expensive.

 

[RooFlyer]

Well you needed a crystal ball to know which of the hundreds of candidates would be first to be deployed. The Fed Gov backed two in a big way and contracted for their manufacture here. One did not make it, but the other is one of the early ones to be deployed.

I thought it was apparent for some months which of the hundreds of vaccine candidates would be the first to be deployed, at least in the West? Pfizer and Oxford/AZ for Australia, as we bought and scheduled them months ago. Not sure what meant by 'backing' (not a criticism, just unsure of the sense), but Australia has or had agreements to take 4 vaccines, 3 now. They put funds directly into the development of the UQ/CSL one, which won't be proceeding; I'm unsure of development funding for any other, other than the COVAX Facility via advance-purchase, which I only discovered in this page:

Australia’s vaccine agreements

The Australian Government has invested a total of over $18 billion in Australia’s vaccine and COVID-19 treatment supply as part of the COVID-19 Health response. Learn more about our vaccine agreements.

www.health.gov.au

I'm generally OK with Australia's timetable but would have preferred the Government to also proceed with 'emergency' evaluation and authorisation as a bit of insurance against a large outbreak between now and March. That is, have it ready to go at short notice for health care workers and those in necessary close-ish contact with infectees if needed, in a substantial outbreak, but otherwise keep to their timetable. A bit each way

 

[tomlee1986]

Or you could look at it this way:

1/ The people who need it most are getting it first. Which is not us in Oz. USA just set a record for deaths in a single day. UK is grim.
2/ That other countries are trialling the vaccines for us.
3/ Emergency approval means that the process is being rushed (though for good reasons in some countries). Australia does not need to rush with the higher risks.

I would wish it to be released sooner like @Pushka said, but I also agree with the points stated above that the world is trialing the vaccines for us now - if we use the emergency approval process, that meant we would not have had the Christmas we did have last week, but with lots of people being sick if not already dead from it

 

[PineappleSkip]

Australia has or had agreements to take 4 vaccines, 3 now.

Australia also has its optional purchase arrangement with COVAX, which is an upfront commitment that allows access the several vaccines under that arrangement. It's flexible, you pay more per dose, but have a more flexible opt out of any vaccine, but does not guarantee supply of a particular number of doses in a particular timeframe.

Then there are countries like South Africa, too rich to qualify for COVAX aid, too poor to purchase vaccines up front, but sophisticated enough to manufacture vaccines - for the West.

For Covid-19 Vaccines, Some Are Too Rich — and Too Poor (Published 2020)

Global inequality is shaping which countries get vaccines first. In South Africa, people’s best chance for vaccines anytime soon is to join an experimental trial.

www.nytimes.com

cheers skip

 

[tomlee1986]

Australia also has an optional purchase arrangement with COVAX, which is an upfront commitment that allows it to opt in to any of the several vaccines under that arrangement. IT's more flexible but does not guarantee supply in a particular timeframe.

cheers skip

i heard of this scheme, but never understood the details of it until now... many thx

 

[lovetravellingoz]

I thought it was apparent for some months which of the hundreds of vaccine candidates would be the first to be deployed, at least in the West? Pfizer and Oxford/AZ for Australia, as we bought and scheduled them months ago. Not sure what meant by 'backing' (not a criticism, just unsure of the sense), but Australia has or had agreements to take 4 vaccines, 3 now. They put funds directly into the development of the UQ/CSL one, which won't be proceeding; I'm unsure of development funding for any other, other than the COVAX Facility via advance-purchase, which I only discovered in this page:

Australia’s vaccine agreements

The Australian Government has invested a total of over $18 billion in Australia’s vaccine and COVID-19 treatment supply as part of the COVID-19 Health response. Learn more about our vaccine agreements.

www.health.gov.au

I'm generally OK with Australia's timetable but would have preferred the Government to also proceed with 'emergency' evaluation and authorisation as a bit of insurance against a large outbreak between now and March. That is, have it ready to go at short notice for health care workers and those in necessary close-ish contact with infectees if needed, in a substantial outbreak, but otherwise keep to their timetable. A bit each way

The link you posted was a recent 22nd Dec 22 Update. By then they had 4 agreements.



The process and early action by the Federal Government that I was referring was the government Tender it called that closed on 20th August.
From that they selected two candidates which were announced on 7th September. The largest of the heads of agreement has been withdrawn.

• Heads of Agreement signed between CSL and the Australian Government to supply 51 million doses of University of Queensland vaccine to Australia, with first doses scheduled for release from mid-2021 following successful clinical trials.
• Heads of Agreement signed between CSL and AstraZeneca for the expected manufacture of approximately 30 million doses of the Oxford University vaccine candidate AZD1222, for supply to Australia with first doses scheduled for release early 2021, following successful clinical trials.
• Funding Deed with the Australian Government and CSL to ready its facilities for the manufacture of the AZD1222 vaccine candidate, and provide an additional COVID-19 vaccine option for Australians

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COVID-19 vaccine and treatment manufacture and supply chain RFI​

Organisation:​	Federal Government​
Issued by:​	Department of Health​
Tender #:​	Health/20-21/RFI​
Location:​	Australian Capital Territory New South Wales : Sydney Queensland : South East Queensland Victoria : Melbourne Metro South Australia : Metropolitan Western Australia : Perth Metropolitan Northern Territory : Darwin​
Category:​	Drugs & Pharmaceutical Products, Medical Equipment & Accessories & Supplies​
Status:​	Closed​
Closing date:​	20-08-2020(closed)​
Description:​	In response to the COVID-19 pandemic, the Australian Government is working to seek early access to and delivery of safe and effective COVID-19 vaccines and treatments as soon as they are available. The Government is conducting an audit of onshore capacity and capability to complement existing information and help inform possible COVID-19 vaccine and treatment manufacturing scenarios. The RFI is seeking information from organisations already regulated or likely to seek regulation through the Therapeutic Goods Administration. It is intended to inform decision making and identify those opportunities which can feasibly be explored to support COVID-19 vaccine and treatments manufacture. This RFI seeks information regarding COVID-19 vaccine and treatment manufacture and supply, in particular, manufacturer current capability and capacity, as well as manufacturer willingness to expand, modify or repurpose capability and capacity to support at population-scale the manufacture of COVID-19 vaccines and treatments.​
​	​
​	This tender has closed.​

My personal view is that the Federal Government has been very proactive, and has continued to be so. They were prudent to initially have backed two different vaccines.

That one of the horses they initially backed fell over is ok. This is not a certain science field. They have continued to be quite nimble and have expanded agreements as time has gone on.

 

[drron]

Well The Minister revealed a very pertinent reason why Australia has not proceeded with Emergency Authorisation apart from the fact there is no Emergency in Australia.Pfizer has not sent all of their supporting evidence to the TGA.
They were granted provisional approval some time ago but all the evidence needs to be assessed before full registration will be granted.
COVID-19 vaccine to help us win the race | Australian Government Department of Health

COVID-19 vaccine provisional determinations | Therapeutic Goods Administration (TGA)

 

[RooFlyer]

Well The Minister revealed a very pertinent reason why Australia has not proceeded with Emergency Authorisation apart from the fact there is no Emergency in Australia.Pfizer has not sent all of their supporting evidence to the TGA.
They were granted provisional approval some time ago but all the evidence needs to be assessed before full registration will be granted.
COVID-19 vaccine to help us win the race | Australian Government Department of Health

COVID-19 vaccine provisional determinations | Therapeutic Goods Administration (TGA)

I don't wish to make a big thing of it, but in response:

* There is no COVID emergency in Australia, but there could be before the March scheduled start. Sure, not as big an emergency as in the UK/US, but if there is a new Victoria-type outbreak (which could be reached in a few weeks with a couple of super-spreader events), you'll be sure that people will be screaming for vaccinations for nursing homes, front-line medicos etc. My point above is that an 'emergency' approval needn't be used before the scheduled release - but it would be handy to have at the ready if things go pear-shaped.

Can you imagine the poo that would be flying if there were hundreds of nursing home deaths in February and the vaccine couldn't be used because the paperwork hadn't been expedited.

* If Pfizer haven't sent the necessary documentation, perhaps they could be persuaded to, if we asked nicely? Possibly they haven't sent because our health mob have said to them 'no hurry, deal with UK etc first, we have months yet'.

all the evidence needs to be assessed before full registration will be granted.

Yes, but the point is how fast is the assessment being progressed. To meet a March timetable, or quicker than normal, or as fast as possible?

Re: COVID-19 vaccine to help us win the race | Australian Government Department of Health ... did you count the clichés?

 

[lovetravellingoz]

And that was great to read recently. Clearly going full on for the Oxford one because the other one is complicated logistically and expensive.

Good to have both (and others) though as one may suit particular demographics or exposures situations better.

ie

• If one reduces transmission then that would be best for people most likely to be exposed such as at present those working in quarantine, aircrew who have to travel international, ship's crews, healthworkers treating CV19 positive patients etc.
• Or one may be better at protecting say the elderly.

 

[drron]

Not one of the candidates have het formally applied to get even provisional registration despite being given pemission to apply in October/November.
If there were a true Emergency in February in Australia then they could and would apply for Emergency Authorisation which wouldn't take long.For the Oxford vaccine that would mean that vaccination could take place virtually immediately as the vaccine is being produced here.

I believe the first of the Pfizer vaccine is being delivered in March.

 

[Pushka]

Well, my Aunts and Uncles in the UK have all had two doses of the current immunisations and they had no issues whatsoever. They are in their nineties. They were in the first batch, and they live in ..... Oxford!

 

[tomlee1986]

Well, my Aunts and Uncles in the UK have all had two doses of the current immunisations and they had no issues whatsoever. They are in their nineties. They were in the first batch, and they live in ..... Oxford!

I wish them all the good health for the next year, as they are in advanced age and this virus can cause long term damage if not death to others especially to those elderly

 

[HappyFlyerFamily]

Well, my Aunts and Uncles in the UK have all had two doses of the current immunisations and they had no issues whatsoever. They are in their nineties. They were in the first batch, and they live in ..... Oxford!

Pfizer?

 

[tomlee1986]

Pfizer?

the only available until now is the Pfizer one... Oxford one is not yet being administered