Given the apparent lack of planning in SA - let's hope the planning for the vaccine distribution logistics is more advanced at the State & Federal Govt level.
The Washington Post has a useful piece on how Pfizer is planning to deal with the -70 C requirement. Unusually, due to mass demand, they propose to supply the vaccine in vials containing 5 doses that then needs to be diluted. Hope that the Fed Govt has been buying up single use syringes specifically for the vaccine - about 50 million when the world (developed) will be after 8 billion of them.
Maybe an email to your local Federal Politician to ensure that single use syringes can't be harvested from Australia for a particular country? Of course they wouldn't do that again would they? No, more like refuse to allow any future production to be exported to Australia to balance the refused imports (two coal carriers have been waiting off China for over 5 months now to be 'processed' & China is refusing to allow their crews to be swapped for new ones).
Cynic, or pragmatist - I foresee diluted doses and a massive global black market springing up as a result of this dilution. If I dilute it an extra 10% I improve my margin 3 fold, an extra 20%...
Each vial of the Pfizer vaccine holds five doses when diluted. Once thawed, the undiluted vial can be kept in a refrigerator for only five days. A diluted vial can be kept for only six hours before it must be discarded.
Now that the relatively 'good news' is above - there was a very revealing interview on ABC Newsradio between 8am-9am this morning with a vaccine expert. The interview was going along very jovially until near the end the journalist asked;
"So what do the results we've seen with 95% efficacy mean?"
Go online & listen, most new revealing information in months - if correct but sounded like it was. Listen to the tone change.
Paraphrasing - it seems that (unstated in the interests of speed & lowering costs) the volunteers for the various vaccine trials are not being physically tested to see if they are now infected with CV. The 95% figure quoted is not actually the efficacy as you and I may think, in some of the media releases note the use of the term 'observed effective' vs 'tested effective'.
It is the inverse of the relative infection rate for people who are showing up as symptomatic. None of the studies (if the lady is correct) are testing to identify unsymptomatic people. Doing the maths, if your study has 40,000+ volunteers being tested weekly then over the first 90 days that's 520,000 tests to be carried out - if you look at some of the countries the volunteers are in then they would account for a significant proportion of the daily testing. Equally they would be spending hours each week to get a test (in some cases).
So there is an argument to support not testing to see if +CV but unsymptomatic. This then makes me wonder whether the volunteers are tested before they enter the trial to see if they already have had CV?
If this is correct then the 'efficacy' at preventing ANY CV infection would seem to be 1/4 to 1/6th the 95% given that typically the ratio of unsymptomatic to symptomatic is quoted as between 3:1 or 5:1.
Not so good
The Washington Post has a useful piece on how Pfizer is planning to deal with the -70 C requirement. Unusually, due to mass demand, they propose to supply the vaccine in vials containing 5 doses that then needs to be diluted. Hope that the Fed Govt has been buying up single use syringes specifically for the vaccine - about 50 million when the world (developed) will be after 8 billion of them.
Maybe an email to your local Federal Politician to ensure that single use syringes can't be harvested from Australia for a particular country? Of course they wouldn't do that again would they? No, more like refuse to allow any future production to be exported to Australia to balance the refused imports (two coal carriers have been waiting off China for over 5 months now to be 'processed' & China is refusing to allow their crews to be swapped for new ones).
Cynic, or pragmatist - I foresee diluted doses and a massive global black market springing up as a result of this dilution. If I dilute it an extra 10% I improve my margin 3 fold, an extra 20%...
Each vial of the Pfizer vaccine holds five doses when diluted. Once thawed, the undiluted vial can be kept in a refrigerator for only five days. A diluted vial can be kept for only six hours before it must be discarded.
Now that the relatively 'good news' is above - there was a very revealing interview on ABC Newsradio between 8am-9am this morning with a vaccine expert. The interview was going along very jovially until near the end the journalist asked;
"So what do the results we've seen with 95% efficacy mean?"
Go online & listen, most new revealing information in months - if correct but sounded like it was. Listen to the tone change.
Paraphrasing - it seems that (unstated in the interests of speed & lowering costs) the volunteers for the various vaccine trials are not being physically tested to see if they are now infected with CV. The 95% figure quoted is not actually the efficacy as you and I may think, in some of the media releases note the use of the term 'observed effective' vs 'tested effective'.
It is the inverse of the relative infection rate for people who are showing up as symptomatic. None of the studies (if the lady is correct) are testing to identify unsymptomatic people. Doing the maths, if your study has 40,000+ volunteers being tested weekly then over the first 90 days that's 520,000 tests to be carried out - if you look at some of the countries the volunteers are in then they would account for a significant proportion of the daily testing. Equally they would be spending hours each week to get a test (in some cases).
So there is an argument to support not testing to see if +CV but unsymptomatic. This then makes me wonder whether the volunteers are tested before they enter the trial to see if they already have had CV?
If this is correct then the 'efficacy' at preventing ANY CV infection would seem to be 1/4 to 1/6th the 95% given that typically the ratio of unsymptomatic to symptomatic is quoted as between 3:1 or 5:1.
Not so good