General Coronavirus chit chat thread - non-travel specific

Another rare disease that may be precipitated by Covid infection.

Case series reports myasthenia gravis associated with SARS-CoV-2 infection

A case series in the Annals of Internal Medicine reports three patients without previous neurologic or autoimmune disorders who were diagnosed with myasthenia gravis after the onset of coronavirus disease 2019 (COVID-19).According to Domenico A. Restivo, MD, Department of Medicine, Neurological...
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And another study with steroi_s showing a lessening of severity with covid.

Study finds methylprednisolone associated with increased ventilator-free days in patients with COVID-19

By Denise BaezNEW YORK -- August 11, 2020 -- Methylprednisolone was associated with increased ventilator-free days and higher probability of extubation in patients with coronavirus disease 2019 (COVID-19), according to a study published in Clinical Infectious Diseases.The retrospective study of...
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drron said:
Another rare disease that may be precipitated by Covid infection.

Case series reports myasthenia gravis associated with SARS-CoV-2 infection

A case series in the Annals of Internal Medicine reports three patients without previous neurologic or autoimmune disorders who were diagnosed with myasthenia gravis after the onset of coronavirus disease 2019 (COVID-19).According to Domenico A. Restivo, MD, Department of Medicine, Neurological...
dgalerts.docguide.com dgalerts.docguide.com
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Oh goody. Another auto immune illness I can develop.

My thoughts are that autoimmune illness can be triggered by genetics (family tendancy); major stress event, or major viral illness. I know I can tick off the first two causing two different illnesses, and my niece developed lupus as a result of the first (tendancy, eg from her father (my sibling) via our mother,) and then viral pneumonia as a teenager where she was very ill in hospital. So Covid is very likely to trigger something. Its just early days of tracking consequences yet.
 
Nephew in law who works in France but escaped to Adelaide to return to his young family in late March has been called to return to France next week. They need to pay a hefty mortgage and so cant just quit. They have two young kids. Usually they travel to see each other every three months. This time - he leaves next Monday currently, he will say goodbye and not know when they will see him again. He wont get enough leave to cover the two weeks quarantine to visit Australia.
 
Ethernet, I am not sure where you are getting your facts.

A bit off topic, so I'll keep it brief.

Thomas Borody has never won a nobel prize. He developed triple H.Pylori therapy.
The prize was won by Barry Marshall and Robin Warren for the discovery of H.Pylori - prior to that gastic ulcers were thought to be secondary to worry and gastric hypersecretion.

I read your article (an interesting read) from the Daily telegraph, hosted on a commercial website promoting its founder (Prof Borody) who specialises in faecal transplants (there are recognised indications for this).

The initial evidence for invermectin on preprint was from registry studies from the surgisphere registry. The same one that was used in the discredited and retracted Lancet and NEJM articles on hydroxychloroquine. A couple of articles in sciencemag and thescientist discuss this. This paper has now been withdrawn.

Following studies, the latest being from Florida. "ICON (Ivermectin in COvid Nineteen) study: Use of Ivermectin is Associated with Lower Mortality in Hospitalized Patients with COVID19" by Cepelowicz Rajter. Again a retrospective cohort study, but it showed an association with a lower mortality. They concluded with "These findings should be further evaluated with randomized controlled trials." So the evidence is in the fledgling stage and needs further investigation, like hundreds of other drugs.

"Dr Borody says he (Pres. Trump) may absorb enough through his skin to protect him, despite people around him at the White House becoming ill." - I would suggest Prof Borody should stick to gastroenterology, as he knows very little about pharmacokinetics. Ivermectin is poorly absorbed though skin, and is very, very unlikely to get to therapeutic levels.

TM
 
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Princess Fiona said:
He’s not a Nobel prize winner.
Can’t find the actual research.
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No he's not. The Nobel for helicobacter went to Barry Marshall and Robin Warren from WA. The Nobel Prize in Physiology or Medicine 2005.

It's interesting how many gastroenterologists seem to be experts in many fields. Remember Andrew Waklefield who was discredited and completely banned from medicine by the GMC for fraud in the UK then went to the US to start a highly paid position at one of their loony "institutes" that still promotes the diswcredited MMR theories.
 
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TheRealTMA said:
No he's not. The Nobel for helicobacter went to Barry Marshall and Robin Warren from WA. The Nobel Prize in Physiology or Medicine 2005.

It's interesting how many gastroenterologists seem to be experts in many fields. Remember Andrew Waklefield who was discredited and completely banned from medicine by the GMC for fraud in the UK then went to the US to start a highly paid position at one of their loony "institutes" that still promotes the diswcredited MMR theories.
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I have very bad memories of a gastroenterologist who almost killed Mr FM :(. He was also a general physician and treated him in emergency, didn’t get him assessed by anyone else, diagnosed brain cancer and discharged him for some R&R. Fortunately we got him over to another hospital where he was assessed by neurologists who them performed life saving therapy for his brain abscesses before they burst and killed him.....
 
So continuing the series of medical articles re Covid.The first I am using will be important for @Pushka.A young woman developing acute SLE with APL antibodies at the same time as becoming Covid positive.

Concomitant new diagnosis of systemic lupus erythematosus and COVID-19 with possible antiphospholipid syndrome. Just a coincidence? A case report and review of intertwining pathophysiology

In the midst of the COVID-19 pandemic, further understanding of its complications points towards dysregulated immune response as a major component. Systemic lupus erythematosus (SLE) is also a disease of immune dysregulation leading to multisystem compromise. We present a case of new-onset SLE...
dgjc.docguide.com dgjc.docguide.com

Next a study of 200 Obstetrics staff in London to see whether they had seroconverted.29 had.!0 were asymptomatic.The commonest symptom was loss of smell.17 had continued to work throughout the pandemic.

Study shows 1 in 6 maternity health professionals have had COVID-19, 35% were completely asymptomatic

By Denise BaezNEW YORK -- August 12, 2020 -- A study that tested 200 obstetric healthcare professionals, including anaesthetists, midwives, and obstetricians, for immune seroconversion found that 14.5% had been infected with severe acute respiratory syndrome coronavirus (SARS‐CoV‐2) as revealed...
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And a study from Sydney University confirming that transmission of Covid in schools is less than for other respiratory viruses.
www.sydney.edu.au

COVID 19 study confirms low transmission in educational settings

New research finds COVID-19 transmission rates in NSW schools and early childcare education and care settings were minimal, particularly between children and from children to adults.
www.sydney.edu.au www.sydney.edu.au
 
drron said:
So continuing the series of medical articles re Covid.The first I am using will be important for @Pushka.A young woman developing acute SLE with APL antibodies at the same time as becoming Covid positive.
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Wow. Thanks for that info. Its hard to determine any causal effect from Covid. She sure had a full on autoimmune response. Will be interesting to see if those tests continue to be so strongly indicative. Lupus anticoagulant being the functional test so possibly the other APS markers being low might suggest it might be transitory. It wasnt with me but can be.
 
And in today's emails another for @Pushka.A study showing a high incidence of lupus anticoagulant in covid patients.

Study finds increased incidence of lupus anticoagulant positivity in patients with COVID-19

A study published in JAMA Network Open found an increased incidence of lupus anticoagulant (LA) positivity in patients with coronavirus disease 2019 (COVID-19). In addition, LA was found to be associated with incidence of thrombosis in patients with COVID-19, after adjusting for C-reactive...
dgalerts.docguide.com dgalerts.docguide.com

An effort by 7 US States to ramp up Antigen testing.
www.coronavirustoday.com

Welcome to Precision Vaccinations News

Precision Vaccinations News publishes vaccine news patients can trust to make informed immunization decisions in partnership with doctors, nurses, and pharmacists.
www.coronavirustoday.com www.coronavirustoday.com

And a very interesting studies that up to half of people with no history of Covid or SARS infection had T cells that recognised 1 or more Covid 19 proteins.Why is unknown but possibly exposure to a common cold corona virus.Could this explain why some have less severe disease.
directorsblog.nih.gov

Immune T Cells May Offer Lasting Protection Against COVID-19

Much of the study on the immune response to SARS-CoV-2, the novel coronavirus that causes COVID-19, has focused on the production of antibodies. But, in fact, immune cells known as memory T cells a…
directorsblog.nih.gov directorsblog.nih.gov
 
drron said:
And in today's emails another for @Pushka.A study showing a high incidence of lupus anticoagulant in covid patients.

Study finds increased incidence of lupus anticoagulant positivity in patients with COVID-19

A study published in JAMA Network Open found an increased incidence of lupus anticoagulant (LA) positivity in patients with coronavirus disease 2019 (COVID-19). In addition, LA was found to be associated with incidence of thrombosis in patients with COVID-19, after adjusting for C-reactive...
dgalerts.docguide.com dgalerts.docguide.com
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Sounds very much like my profile. Maybe I had covid three years ago? 😱😁 I'd be fascinated to see if they have done an ANA for these people.
 
I have found it very interesting to see the number of small home-based businesses starting a roaring trade in masks lately. I am part of several rural-buying pages on Facebook, and it's wild how many people are making masks and selling online. Fabric shops are selling out of elastic and supplies.

I think it's great that people are finding another way to make an income, but some things have certainly concerned me. In particular I saw crochet/knitted ear savers advertised the other day. They take the strain off your ears when wearing masks, which is great, but my concern is that these can't be sanitised.

That said... #shamelessplug ... my brother and sister-in-law are making some fantastic 3d printed ear savers.See here as well as face shields used by a variety of medical and health professionals.

As a crocheter myself I have steered clear of anything COVID related due to concern about litigious Karens and the like, as well as a general dislike for dealing with the general public.
 
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Denali said:
There was a panic buy of sewing machines as well. I bought a couple of the plastic thingys a couple of weeks ago for just in case.
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I was in our local Spotlight this morning, 10am and it was packed !! No distancing - the car park was full, it was C R A Z Y ! 🤪
 
mrs.dr.ron said:
I was in our local Spotlight this morning, 10am and it was packed !! No distancing - the car park was full, it was C R A Z Y ! 🤪
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30% off storewide probably didn't help ;)

The yarn has been flying off the shelves at mine. Everyone took up knitting in iso, apparently!
 
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