General COVID-19 Vaccine Discussion

[DC3]

Israel, especially, has done well.

 

[HappyFlyerFamily]

Yes. And 1.7M doses per day administered on average now, in the US.

About 73% of those aged 65+ have had at least one shot.

Am I misinformed that the current 7-day average is 2.7m per day?

 

[DC3]

Australia by comparison is now delivering an equivalent (adjusted for population) of 0.93M doses - with supply problems and much later start.

And the US has fully vaccinated 16% of their adult population, with 28% having had the first dose.

 

[DC3]

Am I misinformed that the current 7-day average is 2.7m per day?

Good pick-up. Even better. How good is that? Who could have believed the chances of that pre-November 2020?

Edit: Now 2.83M on average, as at today

 

[Must...Fly!]

Good pick-up. Even better. How good is that? Who could have believed the chances of that pre-November 2020?

Edit: Now 2.83M on average, as at today

I would've. The vaccines weren't ordered at the swearing in ceremony.

 

[DC3]

I would've. The vaccines weren't ordered at the swearing in ceremony.

More about the ‘will’ of the administration, I feel. The will to deliver is something else again.

Anyway, the US is doing well, in general

 

[Pushka]

Though all those top countries in the list have way higher death numbers than Australia still.

I know that you continue to use that as a metric to explain the slow vaccination rate but in a global pandemic it isn’t relevant. And if we continued to use that measure then why vaccinate at all? Why would HK Singapore Thailand etc vaccinate. We have PNG literally on our doorstop and so close to indigenous communities. We are a breath and a whisper on that coming into Australia. We have separated families throughout the world and we close Aus state borders in a heart beat. We suspect we have a weapon to pretty much fix all that and still we slumber.

 

[Must...Fly!]

I know that you continue to use that as a metric to explain the slow vaccination rate but in a global pandemic it isn’t relevant.

In a global race for limited vaccine supply it is absolutely relevant. You can't exclude reality.

 

[Pushka]

In a global race for limited vaccine supply it is absolutely relevant. You can't exclude reality.

Sure. But we aren’t using the ones we already have! That’s reality.

 

[drron]

Well the voice of a GP and AMA VP on ABC Breakfast radio discussing the vaccine roll out.

Dr Chris Moy - Progress of the COVID-19 vaccine rollout

Transcript: AMA Vice President, Dr Chris Moy, ABC News Breakfast, Wednesday, 31 March 2021 Subject: Progress of the COVID-19 vaccine rollout

ama.com.au

 

[kpc]

Well the voice of a GP and AMA VP on ABC Breakfast radio discussing the vaccine roll out.

Dr Chris Moy - Progress of the COVID-19 vaccine rollout

Transcript: AMA Vice President, Dr Chris Moy, ABC News Breakfast, Wednesday, 31 March 2021 Subject: Progress of the COVID-19 vaccine rollout

ama.com.au

Chris is a good friend of mine and we go back to med school days. He is very sensible and when I caught up with him last month in Adelaide, he gave me an insight into the politics behind the vaccine rollout...as with the way health is funded. in Australia, the 2 tier (State vs Federal) system is not going well...

 

[jakeseven7]

Chris is a good friend of mine and we go back to med school days. He is very sensible and when I caught up with him last month in Adelaide, he gave me an insight into the politics behind the vaccine rollout...as with the way health is funded. in Australia, the 2 tier (State vs Federal) system is not going well...

Yes the Feds are basically defunding primary care every year via the rebate freeze, putting more and more pressure on acute care State assets which are not designed to handle those volumes.

Its a massive massive structural issue because the two tiers of gov control different levels of healthcare, but the patient journey relies on both.....

 

[drron]

Phfizer COVID vax has been found to be highly effective for adolescents in US trial:​

Pfizer's COVID-19 vaccine found to be 100 per cent effective among adolescents

A study of the Pfizer vaccine shows the jab is highly effective in adolescents aged 12-15 years old, recording higher levels of antibodies than in young adults.

www.abc.net.au

Yes but in that trial there were only 18 infections in the control group.Had there been just 1 positive in the vaccinated group the efficacy would be the same as for other ages at 95%.
If 2 positives in the vaccine group efficacy would fall to under 90%.

See how if there are small numbers trials can produce widely differing results.

But for some more important news on the UK variant.
First it does appear to increase mortality.

Infections with ‘U.K. Variant’ B.1.1.7 Have Greater Risk of Mortality

Since the genome sequence of SARS-CoV-2, the virus responsible for COVID-19, was first reported in January 2020, thousands of variants have been reported. In the vast majority of cases, these varia…

directorsblog.nih.gov

But not huge differencies in the effect of vaccines with this report from the UK on the Oxford vaccine.

Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial

ChAdOx1 nCoV-19 showed reduced neutralisation activity against the B.1.1.7 variant compared with a non-B.1.1.7 variant in vitro, but the vaccine showed efficacy against the B.1.1.7 variant of SARS-CoV-2.

www.thelancet.com

If you read right through the article you may notice this.
"However, a further live coronavirus neutralisation assay showed that sera from BNT162b2 and ChAdOx1 nCoV-19 vaccinees had a 2·0–3·3 times reduction in neutralisation activity against B.1.1.7 compared with the Victoria lineage"
So no significant difference between the Pfizer and Oxford vaccine.
The previous Pfizer studies showing no difference in Neutralising antibodies were comparing it to the original Wuhan virus.This study was with the slightly different virus predominant in the UK before the variant appeared

 

[DC3]

... If you read right through the article you may notice this ...

So, I posted an article.

 

[Flashback]

Same chart by population
View attachment 243838

Post automatically merged: Apr 1, 2021

I mean regarding vaccine roll out

So for every 100 people, Israel has administered doses to 115 of them? Okey dokey then.

 

[Must...Fly!]

This is categorically and 100% false. The first vaccine to be approved and used worldwide was the Pfizer vaccine, which was made in conjunction with Bio n Tech in Germany. They didn't accept a penny from the government and didn't rely on the government in any way, shape or form.

Vaccines, plural.

In any case, you are completely wrong.

Pfizer and BioNTech Announce an Agreement with U.S. Government for up to 600 Million Doses of mRNA-based Vaccine Candidate Against SARS-CoV-2 | Pfizer

U.S. government placed an initial order of 100 million doses for $1.95 billion and can acquire up to 500 million additional doses Americans to receive the vaccine for free consistent with U.S. government’s commitment for free access for COVID-19 vaccines Pfizer and BioNTech remain on track to...

www.pfizer.com

Post automatically merged: Apr 1, 2021

So for every 100 people, Israel has administered doses to 115 of them? Okey dokey then.

Yes - eventually it will be close to 200 as two doses for each. But obviously some will die in the interim (from many varied causes) or have a second dose outside Israel.

 

[hb13]

Vaccines, plural.

In any case, you are completely wrong.

Pfizer and BioNTech Announce an Agreement with U.S. Government for up to 600 Million Doses of mRNA-based Vaccine Candidate Against SARS-CoV-2 | Pfizer

U.S. government placed an initial order of 100 million doses for $1.95 billion and can acquire up to 500 million additional doses Americans to receive the vaccine for free consistent with U.S. government’s commitment for free access for COVID-19 vaccines Pfizer and BioNTech remain on track to...

www.pfizer.com

Post automatically merged: Apr 1, 2021

Yes - eventually it will be close to 200 as two doses for each. But obviously some will die in the interim (from many varied causes) or have a second dose outside Israel.

That's just to purchase vaccines, not the "only reason you have vaccines".

Was the Pfizer vaccine part of the government’s Operation Warp Speed?

That is behind a paywall, but the main part says: "In July, Pfizer got a $1.95 billion deal with the government’s Operation Warp Speed, the multiagency effort to rush a vaccine to market, to deliver 100 million doses of the vaccine. The arrangement is an advance-purchase agreement, meaning that the company won’t get paid until they deliver the vaccines. Pfizer did not accept federal funding to help develop or manufacture the vaccine, unlike front-runners Moderna and AstraZeneca".

 

[Pom-DownUnder]

That's just to purchase vaccines, not the "only reason you have vaccines".

Was the Pfizer vaccine part of the government’s Operation Warp Speed?

That is behind a paywall, but the main part says: "In July, Pfizer got a $1.95 billion deal with the government’s Operation Warp Speed, the multiagency effort to rush a vaccine to market, to deliver 100 million doses of the vaccine. The arrangement is an advance-purchase agreement, meaning that the company won’t get paid until they deliver the vaccines. Pfizer did not accept federal funding to help develop or manufacture the vaccine, unlike front-runners Moderna and AstraZeneca".

Warp Speed also cleared alot of the regulatory hurdles that would usually be in pfizers way, cash or no cash they benefitted from it.

I think the AU rollout will continue to be weak as ..... urine .... EU / UK / USA will get vaccines into their people comparatively quickly and be open and flying around the place which will SHAME the AU gov into opening up as soon as there is good coverage of vaccine.

just my 2c

 

[Pushka]

So for every 100 people, Israel has administered doses to 115 of them? Okey dokey then.

When everyone has had two doses it will be 200 . Except those umm no longer with us. That is the only excuse Israel will except and even then requires a death certificate

 

[DC3]

....just my 2c

Your post is worth much more than that. .

Some good points there by the way.