General Medical issues thread

Rhuematologist update. All blood tests fine except for Thyroid but am used to that. Really high TSH which means my brain is pumping out lots of hormones which is dutifully being ignored by thyroid. Been like that for 30 years now. Maybe an endocrinologist in my future but back on high dose replacement. Psoriasis on scalp but not itching so while it is still apparently extensive it isnt currently itchy so I can ignore it as I can't see it. :eek: Steady as she goes.
 
Rhuematologist update. All blood tests fine except for Thyroid but am used to that. Really high TSH which means my brain is pumping out lots of hormones which is dutifully being ignored by thyroid. Been like that for 30 years now. Maybe an endocrinologist in my future but back on high dose replacement. Psoriasis on scalp but not itching so while it is still apparently extensive it isnt currently itchy so I can ignore it as I can't see it. :eek: Steady as she goes.
Sounds like quite a good report this time which is good to hear. :)
 
Probably the easiest to understand negative feedback biological system is the HPT axis

Hypothalamus-pituitary-thyroid axis

TRH released by hypothalamus in response to low circulating T3/T4 causing release of TSH from pituitary which stimulates thyroid to release t3/T4

Too much T3/t4 negatively feedbacks and slows production of TRH and TSH

Aim of thyroxine replacement is to normalise TSH (assuming pituitary is working)
 
Probably the easiest to understand negative feedback biological system is the HPT axis

Hypothalamus-pituitary-thyroid axis

TRH released by hypothalamus in response to low circulating T3/T4 causing release of TSH from pituitary which stimulates thyroid to release t3/T4

Too much T3/t4 negatively feedbacks and slows production of TRH and TSH

Aim of thyroxine replacement is to normalise TSH (assuming pituitary is working)

Yes. The weird thing was that T3 and T4 were smack in the middle of normal! (On 150 mcg of thyroxine) So why would the pituitary go into overdrive? It's like it's not registering the normal levels? TSH was 46. High is >4. Rheumatologist commented it was the highest she'd seen. As a teen mum had a thyroid storm - the opposite to me.
 
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Yes the body is weird.

How do 5 people in a house come down with flu like symptoms and the person who was sick with another infection not get the flu symptoms? Did they have the flu first which was superceded by other infection?

Mysterious.
 
Yes the body is weird.

How do 5 people in a house come down with flu like symptoms and the person who was sick with another infection not get the flu symptoms? Did they have the flu first which was superceded by other infection?

Mysterious.
I don't like to delve too much into the mysteries of health. It's all too much for me.
 
I don't like to delve too much into the mysteries of health. It's all too much for me.
I don't either but sometimes curiosity takes over. And the interesting thing with the same virus is each person has been affected in a different way. Very confusing.
 
Yes. The weird thing was that T3 and T4 were smack in the middle of normal! (On 150 mcg of thyroxine) So why would the pituitary go into overdrive? It's like it's not registering the normal levels? TSH was 46. High is >4. Rheumatologist commented it was the highest she'd seen. As a teen mum had a thyroid storm - the opposite to me.

Subclinical hypothyroid - hypothyroid in name only because number is not right but clinically not hypothyroid. Sometimes taking massive doses won't change TSH levels. Higher TSH might precipitate an MRI scan for pituitary tumour. Rarely there are TSH antibodies. Mostly it of no issue. Increasing evidence that some need T3

There is another brand with same active ingredient as thyroxine but don't need to refrigerate
 
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Subclinical hypothyroid - hypothyroid in name only because number is not right but clinically not hypothyroid. Sometimes taking massive doses won't change TSH levels. Higher TSH might precipitate an MRI scan for pituitary tumour. Rarely there are TSH antibodies. Mostly it of no issue. Increasing evidence that some need T3

There is another brand with same active ingredient as thyroxine but don't need to refrigerate

Clinically hypothyroid for 30 years but dosage unstable. So upping dosage again due to extreme TSH then retest in 6 weeks. Dr did mention something 'oma' and said results were weird. TSH did reduce last year and that prompted the reduction in dose. Thyroxine does take a bit of space up in the fridge! Big boxes! Have TPO antibodies (>1600; level <100) so autoimmune back 30 years ago.
 
Eltroxin can be stored 25C or less. Does not need to be in fridge.

Similar to Oroxine or Eutroxsig or Thyroxine
Ingredient is levothryxine (synthetic T4)

But don't assume like for like

Cells changes T4 (which has 4 iodine atoms) to T3 (which has 3 iodine atoms) through a de-iodisation process. T3 is the actual active hormone used by the cells
 
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Eltroxin can be stored 25C or less. Does not need to be in fridge.

Similar to Oroxine or Eutroxsig or Thyroxine
Ingredient is levothryxine (synthetic T4)

But don't assume like for like

Cells changes T4 (which has 4 iodine atoms) to T3 (which has 3 iodine atoms) through a de-iodisation process. T3 is the actual active hormone used by the cells
Will have to investigate Eltroxin - keeping thyroid tablets cold when traveling for six months is a pain
 
Getting a man flu bug in Melbourne was an easy way to shed 5 kgs over 2 weeks. Man flu can be quite nasty and my fat cells didn't like it at all.
 
Selena Gomez confirns kidney transplant as a result of Lupus. It's a bu**ar of an illness. Attacks anything!
 
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Man flu has finished but now Mrscove isn't feeling too chipper tonight. That Melbourne bug was quite nasty.
 
My Dad was hospitalised 2 months ago. First it was diagnosed as pneumonia. They discharged him after 5 days and the day of discharge told me it was a "small" heart attack.

After Echo no stents are likely to be required.

They had worries about some enlarged lymph nodes.

Today found out he had prostate cancer which has metastasised into his bones and nodes.

6 months.

whatmeworry, don't know how I missed this initially. Takes me back to my uncle - he's been dead now a year. He lasted 5 months after the final terminal diagnosis. Spend as much time as you can with him. My best wishes to you both
 

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