Australian Reports of the Virus Spread

[Antoallison]

i just caught the ABC news coverage from the USA, about the possibility of using the blood from recovered CV-19 patient donors to help critically ill COVID patients.

Dr David Reich from Mt Sinai is doing investigations using the blood from documented recovered Covid patients who are at least 21 DAYS post infection.
Mayo Clinic is also running trial.

It’s experimental, but may work..any little bit of hope is good.

 

[lovetravellingoz]

is there any information about the doses that would be required to treat Covid-19 ?

That is why there are numerous trials around the world occurring. To determine effectiveness, required does rates etc.



Also the last thing you would want is people trying to self medicate and attempting to gain supplies that may be in limited supply.

 

[lovetravellingoz]

i just caught the ABC news coverage from the USA, about the possibility of using the blood from recovered CV-19 patient donors to help critically ill COVID patients.

Dr David Reich from Mt Sinai is doing investigations using the blood from documented recovered Covid patients who are at least 21 DAYS post infection.
Mayo Clinic is also running trial.

It’s experimental, but may work..any little bit of hope is good.

I listed to a press conference on this several days ago. The impression I gained then it was worth a shot, but they did not sound like they thought it would work.

They are desperate in NY and are trying all sorts of things including having two patients per ventilator (as reportedly also being done in Italy).

 

[I love to travel]

What is the average time from when you catch the virus to when you start to show symptoms?

 

[lovetravellingoz]

What is the average time from when you catch the virus to when you start to show symptoms?

Coronavirus Incubation Period (COVID-19) - Worldometer

Current estimated incubation period (how long it takes for symptoms to appear) for the Novel Coronavirus (2019-nCoV) from Wuhan, China

www.worldometers.info

Summary of findings:

• 2-14 days represents the current official estimated range for the novel coronavirus COVID-19.
• However, a case with an incubation period of 27 days has been reported by Hubei Province local government on Feb. 22 [12]
• In addition, a case with an incubation period of 19 days was observed in a JAMA study of 5 cases published on Feb. 21. [13]
• An outlier of a 24 days incubation period had been for the first time observed in a Feb. 9 study.[11] WHO said at the time that this could actually reflect a second exposure rather than a long incubation period, and that it wasn't going to change its recommendations.
• Period can vary greatly among patients.
• Mean incubation period observed:
  3.0 days (0 - 24 days range, study based on 1,324 cases)
  5.2 days (4.1 - 7.0 days range, based on 425 cases).
• Mean incubation period observed in travelers from Wuhan:
  6.4 days (range from 2.1 to 11.1 days).

COVID-19 Incubation Period
The incubation period (time from exposure to the development of symptoms) of the virus is estimated to be between 2 and 14 days based on the following sources:

• The World Health Organization (WHO) reported an incubation period for COVID-19 between 2 and 10 days. [1]
• China’s National Health Commission (NHC) had initially estimated an incubation period from 10 to 14 days [2].
• The United States' CDC estimates the incubation period for COVID-19 to be between 2 and 14 days [3].
• DXY.cn, a leading Chinese online community for physicians and health care professionals, is reporting an incubation period of "3 to 7 days, up to 14 days".

The estimated range will be most likely narrowed down as more data becomes available.

 

[Pushka]

@drron is there any information about the doses that would be required to treat Covid-19 ? Massive doses for critically ill patients with CV and ARDS, then taper dosage.

Also I am presuming ..based on no information, just a wild guess - that it would be a short term regime for weeks or months, rather than years - so no need for annual eye tests etc

I have read it's a very short course of 10 days or so. Of course, that's Dr Google talking.

Post automatically merged: Mar 28, 2020

That is why there are numerous trials around the world occurring. To determine effectiveness, required does rates etc.



Also the last thing you would want is people trying to self medicate and attempting to gain supplies that may be in limited supply.

Too late for plaquenil. I still have enough for four weeks. And a script waiting for supplies.

 

[drron]

There have been some different dosing regimes those with Plaquenil have used 4-600mg per day in divided doses.Azithromycin 5-600 mg per day-it comes in either 500 or 600 mg here.Problem is some of the trials are not fully reported and no dosage stated and the various case reports usually don't state a dosage.
The 10 day course was in the one small trial reported from France.
But this is why many more studies are being done to see if it works,the dosage and length of treatment.

The interesting one is in the USA where they are seeing if Plaquenil can be used to prevent infection-I guess @Pushka will be happy if that works.

 

[Pushka]

30 new positives in SA, and another 8 linked to Ruby bringing that particular number to 61.

 

[tgh]

It is all so sad….

 

[amaroo]

It is all so sad….

@tgh you post like a well read and positive person.... don't forget that! The wave is coming, but it will wash through. The great majority of us will still be standing, life will go on, and history will record.

 

[tgh]

sigh.. thanks @Amaroo…. much appreciated...
I see both the forest and the trees and it has done well for me in the past.
The awful reality we are all now facing gets to me at times and I feel the pain of the world like a personal wound.
I will , we all will…. carry on , because there is nothing else to do.

 

[Himeno]

Canberra up to 71 cases. 6 in hospital. 2 recovered. Almost 4000 negative tests.
59 linked to overseas travel. 4 from interstate. 7 are close contacts of the above. 1 case under investigation.
No current evidence of community spread in Canberra.

 

[Pushka]

I think we are all on a roller coaster. Highs and lows. Hope and despair.

 

[Tropic]

Friend in cbr advised they are positive yesterday. Flew to BNE return last weekend and sat next to "lovely couple just off a cruise" on the way up. Did the contract tracing interview and now self isolating at home alone....

 

[kyle]

Too late for plaquenil. I still have enough for four weeks. And a script waiting for supplies.

Asked four pharmacies here and no stock. Still have 2 months' supply.

 

[juddles]

What you are talking about is third party physical enforcement - ie beyond the requirements of the ordinary laws which require 'self enforcement' by the citizens (ie don't steal, don't speed), else sanctions applied, such as arrest, and if guilty measures like fines or imprisonment.

So, seriously, what level/type of 'enforcement measures' do you think appropriate? How would you apply them?

This post is consistent with others I have made, when people come on and say 'governments doing it all wrong' or 'should have gone harder, earlier' where they don't post what the correct solution is, and don't seem to have posted weeks or months ago what they are advocating should have been done then.

First up, I am not throwing rocks at the "guvment" - these are difficult times and everyone from the leader to us all is just trying to cope.

But when a government tries to introduce many restrictions that are completely in dis accord with the current generation's standard freedoms, then they have to ensure that there is a serious element to it. Small things help - for example they are just getting on to the necesssity to publicize fines given out to those that ignore the rules.

 

[amaroo]

Daily numbers have started to drop... early days, but it's going in the right direction.

Forget that, Numbers increased today by a record high of 460. Strap yourself in!

 

[amaroo]

Asked four pharmacies here and no stock. Still have 2 months' supply.

That would suggest you are well covered, should stop seeking and leave the stock for others.

 

[RooFlyer]

But when a government tries to introduce many restrictions that are completely in dis accord with the current generation's standard freedoms, then they have to ensure that there is a serious element to it.

Sure, but as I mentioned up thread, how would you enforce adherence to the isolation etc rules if the current frameworks aren't working? If someone is saying 'such-and-such should be done', then there must be at least a concept of how it would work.

How would compliance be enforced? Army/police in every street? What should their actual powers be?

 

[Pushka]

France has approved hydroxychloroquine as an approved treatment drug combined with an antibiotic where necessary. And have banned export in order to avoid stockpiling by a couple of countries.
@drron - I can't see where it is made as the label covers it - and don't want to take off the label. Do you know where it comes from? I know it has to be imported.



Over 20% of SA's cases came from Ruby alone and we have another week to go. From the stats below, initially cruise passengers came from China but that morphed I'd suggest to be travellers from the USA. Cruiselines were very quick to ban passengers from China, Hong Kong, then Korea, Iran and later Italy. They never banned passengers from the USA.

Figures from the National Notifiable Diseases Surveillance System, released to News Corp by the Federal Department of Health, show that of the 3166 infections recorded in Australia by 3pm on Friday:

*19 per cent were acquired in the United States;

*19 per cent were acquired at sea (cruise ships);

*12 per cent were acquired in the United Kingdom;

*An unspecified number of other cases were acquired from 60 other countries and regions.

The weekly report on coronavirus cases to March 14 showed that:

*22 per cent of cases had a direct link to US;

*11 per cent had a direct link to Italy;

*9 per cent had a direct link to Iran;

*8 per cent had a direct link to the UK;

*8 per cent had a direct to China;

*6 per cent were Diamond Princess cruise ship passengers repatriated from Japan;

*37 per cent had a recent travel history to other countries.